HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005886 - plasma membrane GO:0051402 - neuron apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 998
+	Hs
		348673 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1070202 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		349222 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		348528 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		665398 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		665604 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		349904 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		349905 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		349144 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		348527 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665242 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		349903 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		872534 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		350002 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		349123 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		349876 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		349065 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		348472 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		349800 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		349066 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45