HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30196744
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ATG16~Ras
Common GO terms	GO:0005829 - cytosol GO:0043495 - protein-membrane adaptor activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 607
+	Hs
		1070247 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1146825 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		914135 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		350041 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Mm
		1161506 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		919616 RAP1A_HUMAN (1-165): 7.83e-63: 194: 58.08		GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18
+	Mm
		699622 RASK_MOUSE (1-189): 4.5e-77: 230: 98.94		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		903100 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		903508 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		896603 RAB14_HUMAN (4-184): 3.77e-72: 218: 29.51		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Sc
		350806 RAS2_YEAST (3-164): 2.5e-58: 187: 64.42		TAF5_YEAST (129-424): 1.16e-19: 95.5: 9.33