HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: MILK1 (Q8N3F8)
MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13)
Gene: MICALL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 863
+	Mm
		1112011 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		MILK2_MOUSE (6-829): 1.07e-166: 512: 27.96
+	Hs
		349475 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00
+	Hs
		1070295 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00
+	Hs
		348801 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		1070306 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		350362 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		297805 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297829 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		349252 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		297806 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		348621 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164547 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		963331 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164620 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		350082 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		895043 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164548 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		164591 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		1070268 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00
+	Hs
		350290 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00