HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1491
+	Hs
		348876 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MAGI1_HUMAN (1-1491): 0: 756: 100.00
+	Hs
		1020162 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		350121 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (16-556): 6.49e-16: 85.6: 12.05
+	Hs
		349277 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		348639 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		349520 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		349510 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		1021495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		1070320 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		349319 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		350420 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG3_HUMAN (16-556): 6.49e-16: 85.6: 12.05
+	Hs
		348663 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		350124 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		895057 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		1049954 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		350232 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NHRF3_HUMAN (475-719): 9.38e-14: 77.7: 23.08
+	Hs
		350386 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		350374 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		350166 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26