Protein: MD13L
Mediator of RNA polymerase II transcription subunit 13-like (Mediator complex subunit 13-like) (Thyroid hormone receptor-associated protein 2) (Thyroid hormone receptor-associated protein complex 240 kDa component-like)

Gene: MD13L, MED13L
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q71F56

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1174786

MED13
Mediator of RNA polymerase II transcription subunit 13

2

1

High-throughput

0.776

High

826302

CDK8
Cyclin-dependent kinase 8

9

7

High-throughput

0.754

High

48689

MED19
Mediator of RNA polymerase II transcription subunit 19

7

1

High-throughput

0.750

High

1174776

CDK19
Cyclin-dependent kinase 19

6

7

High-throughput

0.733

High

1174774

MED10
Mediator of RNA polymerase II transcription subunit 10

5

1

Small-scale

0.716

High

1076171

MED1
Mediator of RNA polymerase II transcription subunit 1

5

4

Small-scale

0.712

High

1174777

MED28
Mediator of RNA polymerase II transcription subunit 28

5

1

High-throughput

0.712

High

1174779

MED4
Mediator of RNA polymerase II transcription subunit 4

5

2

High-throughput

0.712

High

1174781

MED9
Mediator of RNA polymerase II transcription subunit 9

5

1

Small-scale

0.712

High

624457

CCNC
Cyclin-C

5

4

High-throughput

0.706

High

1037066

MED21
Mediator of RNA polymerase II transcription subunit 21

4

1

High-throughput

0.704

High

206629

MED7
Mediator of RNA polymerase II transcription subunit 7

4

2

High-throughput

0.699

High

1174782

MED29
Mediator of RNA polymerase II transcription subunit 29

4

1

High-throughput

0.699

High

1174762

MED12
Mediator of RNA polymerase II transcription subunit 12

4

4

High-throughput

0.694

High

1174763

FBXW7
F-box/WD repeat-containing protein 7

4

1

Small-scale

0.692

High

1174775

MED18
Mediator of RNA polymerase II transcription subunit 18

3

2

High-throughput

0.675

High

313442

MED26
Mediator of RNA polymerase II transcription subunit 26

3

1

High-throughput

0.667

High

1174791

MED31
Mediator of RNA polymerase II transcription subunit 31

3

2

High-throughput

0.662

High

1174787

MED23
Mediator of RNA polymerase II transcription subunit 23

3

3

High-throughput

0.656

High

225393

MED14
Mediator of RNA polymerase II transcription subunit 14

3

4

High-throughput

0.650

High

1074709

MED22
Mediator of RNA polymerase II transcription subunit 22

3

1

High-throughput

0.650

High

1158897

MED27
Mediator of RNA polymerase II transcription subunit 27

3

1

High-throughput

0.650

High

1174778

MED20
Mediator of RNA polymerase II transcription subunit 20

3

1

High-throughput

0.650

High

1174780

MED17
Mediator of RNA polymerase II transcription subunit 17

3

2

High-throughput

0.650

High

265340

MED24
Mediator of RNA polymerase II transcription subunit 24

2

1

High-throughput

0.611

High

1174783

MED11
Mediator of RNA polymerase II transcription subunit 11

2

2

High-throughput

0.611

High

1018998

TP53B
TP53-binding protein 1

2

2

High-throughput

0.571

High

1174765

MED8
Mediator of RNA polymerase II transcription subunit 8

2

2

High-throughput

0.571

High

1085594

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.536

High

1160871

FXL19
F-box/LRR-repeat protein 19

1

1

High-throughput

0.536

High

1174766

MED30
Mediator of RNA polymerase II transcription subunit 30

1

2

High-throughput

0.536

High

1174773

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.536

High

882933

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.518

High

235920

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

244593

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

270513

MED6
Mediator of RNA polymerase II transcription subunit 6

1

2

High-throughput

0.479

High

487545

ANDR
Androgen receptor

1

7

High-throughput

0.479

High

583510

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

583736

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.479

High

624943

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

676923

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.479

High

738853

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.479

High

854320

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.479

High

913913

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.479

High

1154041

NIPBL
Nipped-B-like protein

1

1

High-throughput

0.479

High

1174756

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

5

High-throughput

0.479

High

1174757

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

1

High-throughput

0.479

High

1174759

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1174770

MED15
Mediator of RNA polymerase II transcription subunit 15

1

2

High-throughput

0.479

High

1174790

MED16
Mediator of RNA polymerase II transcription subunit 16

1

2

High-throughput

0.479

High

1174792

SCC4
MAU2 chromatid cohesion factor homolog

1

1

High-throughput

0.479

High

818182

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

831448

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

91301

E5RFK5
Cyclin-C

1

4

High-throughput

0.445

High

725970

ADDA
Alpha-adducin

1

4

High-throughput

0.445

High

739166

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.445

High

1174771

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.445

High

1173729

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.437

High

232271

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.426

High

505848

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.426

High

1027079

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.426

High

1051230

ZMYM3
Zinc finger MYM-type protein 3

1

0

High-throughput

0.426

High

1174760

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.426

High

73031

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

7

High-throughput

0.407

High

126256

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

3

High-throughput

0.407

High

259647

LIPA2
Liprin-alpha-2

1

1

High-throughput

0.407

High

440590

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.407

High

489767

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.407

High

505994

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

3

High-throughput

0.407

High

675188

CLIP1
CAP-Gly domain-containing linker protein 1

1

1

High-throughput

0.407

High

969493

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

1

High-throughput

0.407

High

1131745

CE170
Centrosomal protein of 170 kDa

1

2

High-throughput

0.407

High

1174768

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

1

High-throughput

0.407

High

1174784

CLIP2
CAP-Gly domain-containing linker protein 2

1

1

High-throughput

0.407

High

1174785

ADDG
Gamma-adducin

1

1

High-throughput

0.407

High

1174788

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

1

High-throughput

0.407

High

1174789

WDR37
WD repeat-containing protein 37

1

3

High-throughput

0.407

High

1174764

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

0

High-throughput

0.279

Low

1174772

SORT
Sortilin

1

0

High-throughput

0.279

Low

949128

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.269

Low

1088537

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.269

Low

499861

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

908730

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1135259

ATD3B
ATPase family AAA domain-containing protein 3B

1

0

High-throughput

0.249

Low

1174767

ZDH15
Palmitoyltransferase ZDHHC15

1

0

Small-scale

0.249

Low

2806

KV108
Immunoglobulin kappa variable 1-8

1

0

High-throughput

0.232

Low

353685

IGHG1
Immunoglobulin heavy constant gamma 1

1

0

High-throughput

0.232

Low

365206

FRIH
Ferritin heavy chain

1

0

High-throughput

0.232

Low

452817

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

781925

PERI
Peripherin

1

0

High-throughput

0.232

Low

981303

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.232

Low

1113948

RABL6
Rab-like protein 6

1

0

High-throughput

0.232

Low

1137876

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

0

High-throughput

0.232

Low

1167214

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.232

Low

1174755

RUFY3
Protein RUFY3

1

0

High-throughput

0.232

Low

1174758

IRGQ
Immunity-related GTPase family Q protein

1

0

High-throughput

0.232

Low

1174761

ARHG2
Rho guanine nucleotide exchange factor 2

1

0

High-throughput

0.232

Low

1174769

ALS2
Alsin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024