HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 759
+	Hs
		918962 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		919684 RAP1A_HUMAN (1-165): 7.83e-63: 194: 58.08		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		897967 RAP1B_HUMAN (1-165): 1.02e-62: 193: 57.49		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1070268 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		350290 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		914166 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		349475 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		1070295 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		918915 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		MICA1_HUMAN (333-572): 7.65e-38: 154: 20.00
+	Hs
		1255762 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		MICA1_HUMAN (333-572): 7.65e-38: 154: 20.00
+	Hs
		845867 RAB13_HUMAN (4-186): 7.7e-72: 217: 36.76		MILK2_HUMAN (295-569): 1.42e-37: 153: 22.95
+	Hs
		350338 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		914208 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		597758 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		CSRP1_HUMAN (254-449): 3.7e-34: 131: 15.82
+	Hs
		845869 RAB13_HUMAN (4-186): 7.7e-72: 217: 36.76		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		857917 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		CRIP2_HUMAN (348-471): 3.86e-29: 117: 27.48
+	Hs
		150501 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		349186 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		348570 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		349323 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00