Protein: DLGP4
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)

Gene: DLGP4, DLGAP4
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q9Y2H0

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0023052 - signaling
GO:0031594 - neuromuscular junction
GO:0050804 - modulation of chemical synaptic transmission
GO:0060090 - molecular adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1417991

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

19

Small-scale

0.791

High

1212220

MPP7
MAGUK p55 subfamily member 7

3

20

High-throughput

0.665

High

320271

SRBS2
Sorbin and SH3 domain-containing protein 2

3

20

Small-scale

0.658

High

440795

FYN
Tyrosine-protein kinase Fyn

3

11

High-throughput

0.653

High

594147

NCK1
SH2/SH3 adapter protein NCK1

3

20

High-throughput

0.653

High

1462614

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

20

Small-scale

0.621

High

1454134

DLGP2
Disks large-associated protein 2

1

6

High-throughput

0.618

High

1006126

DLG4
Disks large homolog 4

2

20

Small-scale

0.613

High

1150506

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

2

20

High-throughput

0.606

High

1325327

PALS1
Protein PALS1

2

20

High-throughput

0.606

High

138539

BIN1
Myc box-dependent-interacting protein 1

1

2

Small-scale

0.586

High

376118

RASK
GTPase KRas

2

3

High-throughput

0.584

High

4756

A0A1B0GTN4
DLG associated protein 2

1

6

High-throughput

0.575

High

222229

NCK2
Cytoplasmic protein NCK2

2

20

High-throughput

0.561

High

162874

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

2

20

High-throughput

0.553

High

848452

MAGA6
Melanoma-associated antigen 6

2

3

High-throughput

0.553

High

943832

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

13

High-throughput

0.553

High

1116625

FHL3
Four and a half LIM domains protein 3

2

5

High-throughput

0.553

High

1206037

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

4

High-throughput

0.553

High

1216169

FHL5
Four and a half LIM domains protein 5

2

5

High-throughput

0.553

High

1452531

ABI2
Abl interactor 2

2

12

High-throughput

0.553

High

167724

LIN7A
Protein lin-7 homolog A

1

20

High-throughput

0.536

High

168773

CSKP
Peripheral plasma membrane protein CASK

1

20

High-throughput

0.536

High

896672

VASP
Vasodilator-stimulated phosphoprotein

1

4

High-throughput

0.536

High

1091603

DLG1
Disks large homolog 1

1

20

High-throughput

0.536

High

1215983

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

1

20

High-throughput

0.536

High

1331381

ENAH
Protein enabled homolog

1

7

High-throughput

0.536

High

1368735

DLG3
Disks large homolog 3

1

20

High-throughput

0.536

High

1418684

PAR6B
Partitioning defective 6 homolog beta

1

8

High-throughput

0.536

High

1450021

LIN7C
Protein lin-7 homolog C

1

20

High-throughput

0.536

High

538144

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

1278994

PRS42
Putative serine protease 42

1

0

High-throughput

0.513

High

1408403

SH3G2
Endophilin-A1

1

13

High-throughput

0.508

High

508860

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.481

High

362417

ABL1
Tyrosine-protein kinase ABL1

1

11

High-throughput

0.479

High

374292

RASN
GTPase NRas

1

3

High-throughput

0.479

High

446092

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

557541

SRC
Proto-oncogene tyrosine-protein kinase Src

1

11

High-throughput

0.479

High

699903

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

4

High-throughput

0.479

High

855812

CRK
Adapter molecule crk

1

19

High-throughput

0.479

High

978416

RHOB
Rho-related GTP-binding protein RhoB

1

2

High-throughput

0.479

High

988048

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

988839

RAC1
Ras-related C3 botulinum toxin substrate 1

1

1

High-throughput

0.479

High

943434

H2BFS
Histone H2B type F-S

1

4

High-throughput

0.470

High

1208913

H2B2F
Histone H2B type 2-F

1

4

High-throughput

0.470

High

1372348

H2B1H
Histone H2B type 1-H

1

4

High-throughput

0.470

High

710580

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.458

High

1159912

OCLN
Occludin

1

0

High-throughput

0.458

High

507429

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

3

High-throughput

0.457

High

1280051

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

16

High-throughput

0.439

High

1448581

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

159928

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.437

High

1256162

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1452848

PLK2
Serine/threonine-protein kinase PLK2

1

3

High-throughput

0.417

High

1367628

ESR2
Estrogen receptor beta

1

1

High-throughput

0.407

High

1316102

A16A1
Aldehyde dehydrogenase family 16 member A1

3

0

High-throughput

0.346

High

276731

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

2

0

High-throughput

0.316

High

1328088

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.316

High

1458908

PPR1B
Protein phosphatase 1 regulatory subunit 1B

1

0

High-throughput

0.282

High

220068

XRCC2
DNA repair protein XRCC2

1

0

High-throughput

0.279

Low

1111998

SNX1
Sorting nexin-1

1

0

High-throughput

0.279

Low

1290193

THOC4
THO complex subunit 4

1

0

High-throughput

0.279

Low

1437889

PRD16
Histone-lysine N-methyltransferase PRDM16

1

0

High-throughput

0.279

Low

1460796

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.279

Low

1490724

DEOC
Deoxyribose-phosphate aldolase

1

0

High-throughput

0.279

Low

1013121

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.269

Low

67184

ZAR1L
Protein ZAR1-like

1

0

High-throughput

0.232

Low

142446

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.232

Low

1449928

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025