Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: ITB8 (P26012)
Integrin beta-8
Gene: ITGB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_beta~TGFb_propeptide
Common GO terms GO:0001570 - vasculogenesis
GO:0005886 - plasma membrane
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0009986 - cell surface
GO:0010628 - positive regulation of gene expression
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 390
Hs

1 769
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024