Interactor 1: PENK (P01210)
Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); PENK(114-133); PENK(143-183); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; PENK(237-258); Met-enkephalin-Arg-Phe]
Gene: PENK

Interactor 2: PDYN (P01213)
Proenkephalin-B (Beta-neoendorphin-dynorphin) (Preprodynorphin) [Cleaved into: Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin (Big Dyn); Dynorphin A(1-17) (Dyn-A17) (Dynorphin A); Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; Rimorphin (Dynorphin B) (Dyn-B) (Dynorphin B(1-13)); Leumorphin (Dynorphin B-29)]
Gene: PDYN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.55 0.585

The method score is based on:

Property Details
Experiments 26186194, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001515 - opioid peptide activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007218 - neuropeptide signaling pathway
GO:0007268 - chemical synaptic transmission
and 5 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024