HitPredict

Interactor 1: TNFA (P01375)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: TNF

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27545878
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 344
+	Hs
		352696 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Mm
		420393 TNFA_MOUSE (1-233): 1.68e-95: 280: 78.81		TIA1_MOUSE (2-335): 1.54e-33: 129: 15.46
+	Hs
		352462 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		352581 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Mm
		420394 TNFA_MOUSE (1-233): 1.68e-95: 280: 78.81		TIAR_MOUSE (2-120): 5.05e-13: 71.5: 17.89