HitPredict

Interactor 1: IFNA7 (P01567)
Interferon alpha-7 (IFN-alpha-7) (Interferon alpha-J) (LeIF J) (Interferon alpha-J1) (IFN-alpha-J1)
Gene: IFNA7

Interactor 2: IFIT1 (P09914)
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
Gene: IFIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009615 - response to virus GO:0051607 - defense response to virus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 478
+	Hs
		352824 IFNA5_HUMAN (1-189): 3.92e-105: 301: 79.89		IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00
+	Hs
		352779 IFN10_HUMAN (1-189): 2.34e-103: 296: 92.06		IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00
+	Hs
		352798 IFN21_HUMAN (1-189): 2.07e-102: 294: 87.83		IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00
+	Hs
		352836 IFN14_HUMAN (1-189): 3.66e-101: 291: 80.95		IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00
+	Hs
		456259 IFNA8_HUMAN (1-189): 3.68e-96: 278: 77.78		IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00
+	Hs
		157401 IFNA5_HUMAN (1-189): 3.92e-105: 301: 79.89		IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73
+	Hs
		157400 IFN21_HUMAN (1-189): 2.07e-102: 294: 87.83		IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73
+	Hs
		157399 IFNA7_HUMAN (1-189): 1.94e-101: 291: 100.00		IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73
+	Hs
		157402 IFN14_HUMAN (1-189): 3.66e-101: 291: 80.95		IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73
+	Hs
		157398 IFNA2_HUMAN (1-189): 5.51e-96: 278: 77.78		IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73
+	Hs
		157428 IFNA8_HUMAN (1-189): 3.68e-96: 278: 77.78		IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73