Protein: F107A
Actin-associated protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A)

Gene: F107A, FAM107A
Organism: Homo sapiens
Interactions: 74
UniProt ID: O95990

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352762

TRAF2
TNF receptor-associated factor 2

4

1

High-throughput

0.692

High

51391

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

1

High-throughput

0.628

High

352770

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

0

High-throughput

0.622

High

323067

TRI37
E3 ubiquitin-protein ligase TRIM37

2

0

High-throughput

0.618

High

352784

IKBD
NF-kappa-B inhibitor delta

2

1

High-throughput

0.606

High

343723

LDOC1
Protein LDOC1

2

0

High-throughput

0.582

High

352757

ERR3
Estrogen-related receptor gamma

2

0

High-throughput

0.580

High

352769

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.580

High

352777

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.580

High

352800

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

1

High-throughput

0.573

High

352776

K1C27
Keratin, type I cytoskeletal 27

2

2

High-throughput

0.553

High

352782

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.549

High

352748

K1C15
Keratin, type I cytoskeletal 15

1

2

High-throughput

0.541

High

352786

ANR49
Ankyrin repeat domain-containing protein 49

1

1

High-throughput

0.536

High

352779

COMD1
COMM domain-containing protein 1

1

0

Small-scale

0.529

High

352774

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.523

High

283412

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.518

High

352742

VIME
Vimentin

1

0

High-throughput

0.518

High

352763

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.518

High

352767

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

352790

HOOK2
Protein Hook homolog 2

1

0

High-throughput

0.518

High

352796

BEGIN
Brain-enriched guanylate kinase-associated protein

1

0

High-throughput

0.518

High

352753

DAPK1
Death-associated protein kinase 1

1

0

High-throughput

0.513

High

193078

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

0

High-throughput

0.513

High

352746

SPTB1
Spectrin beta chain, erythrocytic

1

0

High-throughput

0.513

High

352752

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.513

High

352785

LMO3
LIM domain only protein 3

1

0

High-throughput

0.513

High

352743

K1C19
Keratin, type I cytoskeletal 19

1

2

High-throughput

0.494

High

352799

FKBPL
FK506-binding protein-like

1

1

High-throughput

0.489

High

60150

HFM1
Probable ATP-dependent DNA helicase HFM1

1

2

Small-scale

0.481

High

276656

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

1

Small-scale

0.481

High

352751

MTREX
Exosome RNA helicase MTR4

1

1

Small-scale

0.481

High

352772

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.480

High

352755

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.479

High

180460

PLS1
Phospholipid scramblase 1

1

0

Small-scale

0.460

High

352745

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.460

High

352756

IF4A1
Eukaryotic initiation factor 4A-I

1

0

Small-scale

0.460

High

352760

HSP7E
Heat shock 70 kDa protein 14

1

0

Small-scale

0.460

High

352761

NEXN
Nexilin

1

0

Small-scale

0.460

High

352778

MEIOB
Meiosis-specific with OB domain-containing protein

1

0

Small-scale

0.460

High

352787

APBP2
Amyloid protein-binding protein 2

1

0

Small-scale

0.460

High

352792

BIRC8
Baculoviral IAP repeat-containing protein 8

1

0

Small-scale

0.460

High

352797

AZI2
5-azacytidine-induced protein 2

1

0

Small-scale

0.460

High

352802

POMP
Proteasome maturation protein

1

0

Small-scale

0.460

High

352744

THIO
Thioredoxin

1

0

High-throughput

0.458

High

352747

PYRG1
CTP synthase 1

1

0

High-throughput

0.458

High

352749

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

352754

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

352804

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.458

High

352791

CC136
Coiled-coil domain-containing protein 136

3

0

High-throughput

0.348

High

352780

USBP1
Harmonin-binding protein USHBP1

2

0

High-throughput

0.337

High

65001

GG6L9
Golgin subfamily A member 6-like protein 9

2

0

High-throughput

0.316

High

269139

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

352775

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.299

High

352794

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.299

High

351497

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

0

High-throughput

0.282

High

352793

KR412
Keratin-associated protein 4-12

1

0

High-throughput

0.282

High

352803

NINL
Ninein-like protein

1

0

High-throughput

0.282

High

352766

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.279

Low

352758

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.269

Low

352759

DCD
Dermcidin

1

0

High-throughput

0.269

Low

352768

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.269

Low

352750

ITPI2
Protein ITPRID2

1

0

Small-scale

0.251

Low

352764

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

Small-scale

0.251

Low

352765

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

Small-scale

0.251

Low

352771

EFHC2
EF-hand domain-containing family member C2

1

0

Small-scale

0.251

Low

352773

RNLS
Renalase

1

0

Small-scale

0.251

Low

352781

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

Small-scale

0.251

Low

352783

SPT22
Spermatogenesis-associated protein 22

1

0

Small-scale

0.251

Low

352788

HTRA1
Serine protease HTRA1

1

0

Small-scale

0.251

Low

352789

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

0

Small-scale

0.251

Low

352795

GDAH
Guanidino acid hydrolase, mitochondrial

1

0

Small-scale

0.251

Low

352798

RAB18
Ras-related protein Rab-18

1

0

Small-scale

0.251

Low

352801

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

0

Small-scale

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025