HitPredict

Interactor 1: IFNG (P01579)
Interferon gamma (IFN-gamma) (Immune interferon)
Gene: IFNG

Interactor 2: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15522880, 18641343
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 331
+	Mm
		352940 IFNG_MOUSE (1-156): 9.95e-80: 234: 41.03		JUN_MOUSE (1-331): 5.76e-86: 263: 94.61
+	Hs
		352914 IFNG_HUMAN (1-166): 4.25e-90: 261: 100.00		ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33
+	Hs
		352926 IFNG_HUMAN (1-166): 4.25e-90: 261: 100.00		CREM_HUMAN (54-303): 2.27e-31: 122: 16.48
+	Hs
		352915 IFNG_HUMAN (1-166): 4.25e-90: 261: 100.00		CREB1_HUMAN (54-307): 2.89e-29: 116: 14.84
+	Hs
		352916 IFNG_HUMAN (1-166): 4.25e-90: 261: 100.00		ATF1_HUMAN (42-306): 1.3e-26: 107: 13.97