Interactor 1: CD8A (P01731)
T-cell surface glycoprotein CD8 alpha chain (T-cell surface glycoprotein Lyt-2) (CD antigen CD8a)
Gene: CD8A

Interactor 2: ZAP70 (P43404)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15143214
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0019722 - calcium-mediated signaling
GO:0050850 - positive regulation of calcium-mediated signaling
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 247
Mm

1 618
+ Mm

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Last updated: 15 Jul 2024