HitPredict

Interactor 1: IFNB (P01574)
Interferon beta (IFN-beta) (Fibroblast interferon)
Gene: IFNB1

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	15699120, 16984921, 10848607, 16014923, 11090630, 22531926
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019221 - cytokine-mediated signaling pathway GO:0045087 - innate immune response GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051607 - defense response to virus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 187 Hs			1 551
+	Mm
		352896 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		TF65_MOUSE (1-551): 0: 577: 87.88
+	Hs
		352880 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		352866 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		352877 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Mm
		352889 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		NFKB1_MOUSE (7-451): 3.1e-157: 475: 30.19
+	Mm
		352897 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		RELB_MOUSE (13-461): 1.29e-154: 455: 38.72
+	Mm
		352905 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		NFKB2_MOUSE (7-408): 3.28e-134: 413: 34.36