HitPredict

Interactor 1: HV333 (P01772)
Immunoglobulin heavy variable 3-33 (Ig heavy chain V-III region HIL) (Ig heavy chain V-III region KOL)
Gene: IGHV3-33

Interactor 2: IGLC1 (P0CG04)
Immunoglobulin lambda constant 1 (Ig lambda chain C region MGC) (Ig lambda-1 chain C region)
Gene: IGLC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	2713105
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~V-set
Common GO terms	GO:0003823 - antigen binding GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0006955 - immune response GO:0016064 - immunoglobulin mediated immune response and 1 others more... GO:0072562 - blood microparticle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 106
+	Mm
		353343 HVM02_MOUSE (1-117): 1.7e-47: 150: 44.44		IGKC_MOUSE (5-105): 4.42e-34: 115: 41.35
+	Mm
		526804 VPREB_MOUSE (1-116): 8.52e-41: 133: 29.92		IGLL1_MOUSE (1-106): 8.04e-38: 127: 67.93
+	Mm
		353578 HVM57_MOUSE (20-117): 5.23e-45: 142: 75.51		IGKC_MOUSE (5-105): 4.42e-34: 115: 41.35
+	Hs
		353209 LV208_HUMAN (1-116): 7.34e-35: 118: 28.21		IGLC1_HUMAN (1-106): 4.95e-41: 132: 100.00
+	Mm
		353352 HVM32_MOUSE (20-115): 7.41e-40: 130: 65.31		IGKC_MOUSE (5-105): 4.42e-34: 115: 41.35
+	Mm
		353344 HVM03_MOUSE (21-117): 4.57e-38: 126: 48.45		IGKC_MOUSE (5-105): 4.42e-34: 115: 41.35
+	Mm
		353351 HVM20_MOUSE (20-117): 1.05e-37: 125: 67.00		IGKC_MOUSE (5-105): 4.42e-34: 115: 41.35
+	Hs
		353350 HV307_HUMAN (1-117): 1.53e-55: 170: 87.18		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353347 HV323_HUMAN (1-117): 3.23e-55: 169: 85.47		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353871 HV431_HUMAN (1-117): 5.71e-39: 128: 47.90		IGHG4_HUMAN (7-104): 2.26e-11: 60.4: 25.96
+	Hs
		353750 HV431_HUMAN (1-117): 5.71e-39: 128: 47.90		IGHG2_HUMAN (4-91): 3.46e-11: 60: 29.55
+	Hs
		353837 HV431_HUMAN (1-117): 5.71e-39: 128: 47.90		IGHG3_HUMAN (7-104): 4.37e-11: 59.6: 24.04
+	Hs
		353698 Q8N355_HUMAN (1-116): 2.12e-37: 128: 26.72		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353180 KVD40_HUMAN (6-117): 2.38e-37: 124: 23.08		IGHM_HUMAN (7-93): 9.01e-10: 55.8: 36.26
+	Hs
		353208 LV208_HUMAN (1-116): 7.34e-35: 118: 28.21		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353204 LV147_HUMAN (1-116): 1.03e-33: 114: 27.59		IGHM_HUMAN (7-93): 9.01e-10: 55.8: 36.26
+	Hs
		353203 LV147_HUMAN (1-116): 1.03e-33: 114: 27.59		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04