Protein: RFOX1
RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A) (Hexaribonucleotide-binding protein 1)

Gene: RFOX1, RBFOX1
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q9NWB1

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1372101

RBPMS
RNA-binding protein with multiple splicing

4

6

High-throughput

0.911

High

211437

RFOX2
RNA binding protein fox-1 homolog 2

2

17

High-throughput

0.815

High

65318

RFOX3
RNA binding protein fox-1 homolog 3

2

18

Small-scale

0.806

High

48093

RBM47
RNA-binding protein 47

2

18

High-throughput

0.783

High

1253988

RBPS2
RNA-binding protein with multiple splicing 2

2

6

High-throughput

0.783

High

913068

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

18

High-throughput

0.698

High

1451149

RFOX1
RNA binding protein fox-1 homolog 1

1

17

High-throughput

0.698

High

1139148

DAZP2
DAZ-associated protein 2

3

2

High-throughput

0.667

High

1416489

RBM24
RNA-binding protein 24

1

20

High-throughput

0.656

High

155033

BHE40
Class E basic helix-loop-helix protein 40

3

4

High-throughput

0.654

High

927579

ATX1
Ataxin-1

2

7

High-throughput

0.639

High

1410991

RHXF2
Rhox homeobox family member 2

2

3

High-throughput

0.636

High

162715

ANM5
Protein arginine N-methyltransferase 5

2

16

High-throughput

0.628

High

1338076

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

2

1

High-throughput

0.628

High

1446867

COPRS
Coordinator of PRMT5 and differentiation stimulator

2

2

High-throughput

0.628

High

1211523

CELF3
CUGBP Elav-like family member 3

1

20

High-throughput

0.621

High

1451155

MAGD1
Melanoma-associated antigen D1

2

13

High-throughput

0.620

High

1406503

ATX2
Ataxin-2

2

13

High-throughput

0.620

High

132521

CDC7
Cell division cycle 7-related protein kinase

1

9

High-throughput

0.618

High

136142

PLK4
Serine/threonine-protein kinase PLK4

1

10

High-throughput

0.618

High

1101059

G3BP1
Ras GTPase-activating protein-binding protein 1

1

20

High-throughput

0.618

High

1127195

RBM39
RNA-binding protein 39

1

20

High-throughput

0.618

High

1401053

PHF12
PHD finger protein 12

1

17

High-throughput

0.618

High

1364831

F168A
Protein FAM168A

3

5

High-throughput

0.609

High

505619

ATX1L
Ataxin-1-like

2

7

High-throughput

0.606

High

1044713

ARI5A
AT-rich interactive domain-containing protein 5A

2

1

High-throughput

0.606

High

1133182

LASP1
LIM and SH3 domain protein 1

2

8

High-throughput

0.606

High

1397219

SMIP9
Protein SPMIP9

2

1

High-throughput

0.606

High

1429863

TOLIP
Toll-interacting protein

2

1

High-throughput

0.606

High

1384578

RNF25
E3 ubiquitin-protein ligase RNF25

2

0

High-throughput

0.602

High

1413527

Q9BTF3
TNRC4 protein

1

19

High-throughput

0.590

High

1241247

CA094
Uncharacterized protein C1orf94

2

3

High-throughput

0.590

High

1451156

NUMBL
Numb-like protein

1

2

High-throughput

0.582

High

1277249

POGZ
Pogo transposable element with ZNF domain

2

0

High-throughput

0.580

High

1437363

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.575

High

261666

CATL2
Cathepsin L2

2

2

High-throughput

0.574

High

1309624

SPA12
Serpin A12

2

1

High-throughput

0.574

High

928355

ATN1
Atrophin-1

1

14

High-throughput

0.573

High

1400081

QKI
KH domain-containing RNA-binding protein QKI

1

20

High-throughput

0.573

High

531159

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

6

High-throughput

0.571

High

1408417

SH3G3
Endophilin-A3

2

7

High-throughput

0.571

High

128559

SIRB1
Signal-regulatory protein beta-1

2

4

High-throughput

0.553

High

330344

VENTX
Homeobox protein VENTX

2

3

High-throughput

0.553

High

353586

AGR2
Anterior gradient protein 2 homolog

2

3

High-throughput

0.553

High

1278578

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

1

High-throughput

0.553

High

159881

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

6

High-throughput

0.541

High

210128

CRX
Cone-rod homeobox protein

1

4

High-throughput

0.541

High

286412

DAB1
Disabled homolog 1

1

2

High-throughput

0.541

High

991260

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

8

High-throughput

0.541

High

1397926

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

2

High-throughput

0.541

High

1402786

STRBP
Spermatid perinuclear RNA-binding protein

1

20

High-throughput

0.541

High

926234

ICLN
Methylosome subunit pICln

1

2

High-throughput

0.536

High

1117999

PKP1
Plakophilin-1

1

10

High-throughput

0.536

High

1451152

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

15

High-throughput

0.536

High

1363761

PSMF1
Proteasome inhibitor PI31 subunit

1

1

High-throughput

0.532

High

384564

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.515

High

386293

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.515

High

1289899

Q86V38
Atrophin 1

1

10

High-throughput

0.515

High

1369708

KLK6
Kallikrein-6

1

2

High-throughput

0.515

High

161892

IMPA2
Inositol monophosphatase 2

1

0

High-throughput

0.513

High

704459

GRAN
Grancalcin

1

4

High-throughput

0.508

High

875803

PRC2A
Protein PRRC2A

1

20

High-throughput

0.508

High

944905

PCBP4
Poly(rC)-binding protein 4

1

20

High-throughput

0.508

High

1451151

HSFX1
Heat shock transcription factor, X-linked

1

5

High-throughput

0.508

High

1369539

KIFA3
Kinesin-associated protein 3

1

11

High-throughput

0.494

High

1397060

HSFY1
Heat shock transcription factor, Y-linked

1

5

High-throughput

0.494

High

1411337

LZTS2
Leucine zipper putative tumor suppressor 2

1

16

High-throughput

0.494

High

1396694

CPNS2
Calpain small subunit 2

1

4

High-throughput

0.489

High

1411733

RIOK1
Serine/threonine-protein kinase RIO1

1

6

High-throughput

0.489

High

1451153

NOC2L
Nucleolar complex protein 2 homolog

1

1

High-throughput

0.481

High

294415

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

872801

SOX2
Transcription factor SOX-2

1

14

High-throughput

0.479

High

905197

MECP2
Methyl-CpG-binding protein 2

1

9

High-throughput

0.479

High

1060581

KLC1
Kinesin light chain 1

1

8

High-throughput

0.479

High

1152483

T22D1
TSC22 domain family protein 1

1

9

High-throughput

0.479

High

1255792

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1357162

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

1367409

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1397486

CI072
Guanine nucleotide exchange factor C9orf72

1

8

High-throughput

0.479

High

1405618

TSNAX
Translin-associated protein X

1

1

High-throughput

0.479

High

1429371

SPRTN
DNA-dependent metalloprotease SPRTN

1

2

High-throughput

0.479

High

1451154

TRRAP
Transformation/transcription domain-associated protein

1

3

High-throughput

0.479

High

109520

G5E9A7
DM1 locus, WD repeat containing

1

17

High-throughput

0.470

High

650451

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.470

High

1138099

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.464

High

1437672

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.462

High

1451150

HYPK
Huntingtin-interacting protein K

1

0

High-throughput

0.460

High

3487

A0A0S2Z5K8
Spermatid perinuclear RNA-binding protein

1

20

High-throughput

0.457

High

1437148

Q9H9J5
cDNA FLJ12694 fis, clone NT2RP1000358, highly similar to Homo sapiens mRNA; cDNA DKFZp564C186

1

1

High-throughput

0.457

High

1017757

PR20A
Proline-rich protein 20A

1

7

High-throughput

0.439

High

1445954

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

13

High-throughput

0.439

High

1399141

CF418
Cilia- and flagella-associated protein 418

1

0

Small-scale

0.438

High

867457

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.437

High

1178423

CL16A
Protein CLEC16A

1

2

High-throughput

0.437

High

1017623

PR20C
Proline-rich protein 20C

1

7

High-throughput

0.417

High

327702

UBL3
Ubiquitin-like protein 3

2

0

High-throughput

0.316

High

652425

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

1159424

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1416757

BBS2
BBSome complex member BBS2

1

0

High-throughput

0.279

Low

1292940

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025