HitPredict

Interactor 1: IGKC (P01834)
Immunoglobulin kappa constant (Ig kappa chain C region) (Ig kappa chain C region AG) (Ig kappa chain C region CUM) (Ig kappa chain C region EU) (Ig kappa chain C region OU) (Ig kappa chain C region ROY) (Ig kappa chain C region TI)
Gene: IGKC

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25480565, 22020283
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 107 Hs			1 119
+	Hs
		382467 Q860B5_HUMAN (1-105): 1.04e-38: 132: 20.95		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41
+	Hs
		382258 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41
+	Hs
		354627 HLAH_HUMAN (1-105): 1.47e-37: 131: 20.95		HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66
+	Hs
		382277 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66
+	Hs
		82385 IGLL5_HUMAN (4-107): 1.07e-39: 132: 36.54		HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00
+	Hs
		354240 HLAH_HUMAN (1-105): 1.47e-37: 131: 20.95		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		354248 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		354631 HLAH_HUMAN (1-105): 1.47e-37: 131: 20.95		HLAG_HUMAN (2-116): 6.98e-44: 147: 22.41
+	Mm
		354229 HA1L_MOUSE (2-105): 4.96e-39: 135: 18.27		B2MG_MOUSE (1-119): 1.64e-43: 140: 68.07
+	Hs
		354804 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		DQA1_HUMAN (20-119): 4.08e-43: 143: 27.72
+	Mm
		354230 HA11_MOUSE (2-105): 1.08e-38: 133: 18.27		B2MG_MOUSE (1-119): 1.64e-43: 140: 68.07
+	Mm
		354235 HA17_MOUSE (2-106): 2.04e-38: 132: 20.00		B2MG_MOUSE (1-119): 1.64e-43: 140: 68.07
+	Hs
		92644 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		E9PMV2_HUMAN (20-115): 5.18e-43: 141: 30.93
+	Mm
		354231 HA12_MOUSE (2-106): 9.64e-38: 131: 20.00		B2MG_MOUSE (1-119): 1.64e-43: 140: 68.07
+	Hs
		354630 HLAH_HUMAN (1-105): 1.47e-37: 131: 20.95		HLAE_HUMAN (3-117): 8.23e-41: 140: 22.03
+	Hs
		382286 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		HLAE_HUMAN (3-117): 8.23e-41: 140: 22.03
+	Hs
		901892 Q95J06_HUMAN (1-105): 6.36e-39: 134: 20.95		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		901879 Q5SUL5_HUMAN (1-103): 8.67e-38: 131: 21.36		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		355008 HLAA_HUMAN (1-103): 1.41e-37: 131: 21.36		DQB1_HUMAN (13-115): 4.62e-40: 135: 29.81
+	Rn
		421721 HA12_RAT (2-105): 1.04e-37: 131: 17.31		B2MG_RAT (1-119): 7.63e-41: 133: 69.75