HitPredict

Interactor 1: DRA (P01903)
HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)
Gene: HLA-DRA

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20458337
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0023026 - MHC class II protein complex binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 254 Hs			1 646
+	Hs
		354628 HLAH_HUMAN (32-252): 1.09e-71: 225: 16.81		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		46275 A0A1V1IGJ9_HUMAN (2-222): 5.9e-73: 225: 21.74		HS71A_HUMAN (1-646): 0: 948: 84.37
+	Hs
		354924 DRB1_HUMAN (1-222): 1.19e-69: 216: 19.91		HS71A_HUMAN (1-646): 0: 948: 84.37
+	Hs
		503351 DRB4_HUMAN (61-218): 4.5e-59: 189: 25.27		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504167 DRB5_HUMAN (13-218): 8.37e-58: 186: 21.30		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		503885 DRB3_HUMAN (69-218): 1.81e-55: 180: 26.90		HSP7C_HUMAN (1-646): 0: 967: 100.00