Protein: RNF6
E3 ubiquitin-protein ligase RNF6 (EC 2.3.2.27)

Gene: RNF6
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9Y252

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849491

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

Small-scale

0.778

High

909343

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

135962

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

1377020

RNF6
E3 ubiquitin-protein ligase RNF6

1

17

Small-scale

0.647

High

456372

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

5

High-throughput

0.628

High

487855

ANDR
Androgen receptor

1

8

Small-scale

0.604

High

551320

ITF2
Transcription factor 4

2

1

Small-scale

0.586

High

665969

PTN6
Tyrosine-protein phosphatase non-receptor type 6

2

10

Small-scale

0.584

High

980915

TLE3
Transducin-like enhancer protein 3

2

3

Small-scale

0.584

High

804158

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

1

Small-scale

0.578

High

1023141

STK4
Serine/threonine-protein kinase 4

1

1

Small-scale

0.561

High

1037496

ASAH1
Acid ceramidase

1

1

High-throughput

0.536

High

1336181

CPNE5
Copine-5

1

1

High-throughput

0.536

High

387763

P53
Cellular tumor antigen p53

1

7

Small-scale

0.501

High

1316997

LOXE3
Hydroperoxide isomerase ALOXE3

1

5

High-throughput

0.489

High

216609

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

3

High-throughput

0.481

High

266452

TAD2A
Transcriptional adapter 2-alpha

1

2

High-throughput

0.481

High

302053

TRI37
E3 ubiquitin-protein ligase TRIM37

1

11

High-throughput

0.481

High

320751

LDOC1
Protein LDOC1

1

1

High-throughput

0.481

High

537137

TRI27
Zinc finger protein RFP

1

8

High-throughput

0.481

High

580123

K1C15
Keratin, type I cytoskeletal 15

1

6

High-throughput

0.481

High

734815

TRI23
E3 ubiquitin-protein ligase TRIM23

1

20

High-throughput

0.481

High

838361

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

981786

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.481

High

1033765

IKZF1
DNA-binding protein Ikaros

1

4

High-throughput

0.481

High

1100953

MOONR
Protein moonraker

1

3

High-throughput

0.481

High

1102821

CCD57
Coiled-coil domain-containing protein 57

1

4

High-throughput

0.481

High

1127215

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

3

High-throughput

0.481

High

1144654

TENS2
Tensin-2

1

3

High-throughput

0.481

High

1254187

MIPO1
Mirror-image polydactyly gene 1 protein

1

1

High-throughput

0.481

High

1289578

HOOK2
Protein Hook homolog 2

1

6

High-throughput

0.481

High

1306297

MDFI
MyoD family inhibitor

1

2

High-throughput

0.481

High

1318467

TSG10
Testis-specific gene 10 protein

1

6

High-throughput

0.481

High

1353895

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.481

High

1356052

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

15

High-throughput

0.481

High

1356581

IKZF3
Zinc finger protein Aiolos

1

5

High-throughput

0.481

High

1377022

MAGD1
Melanoma-associated antigen D1

1

12

High-throughput

0.481

High

150640

ABLM1
Actin-binding LIM protein 1

1

1

High-throughput

0.479

High

214696

MYO1B
Unconventional myosin-Ib

1

5

High-throughput

0.479

High

303749

ZO3
Tight junction protein ZO-3

1

2

High-throughput

0.479

High

370740

ESR1
Estrogen receptor

1

8

Small-scale

0.479

High

377815

GCR
Glucocorticoid receptor

1

8

Small-scale

0.479

High

391484

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

3

High-throughput

0.479

High

444812

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

3

High-throughput

0.479

High

670495

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

3

High-throughput

0.479

High

717444

CTNB1
Catenin beta-1

1

3

High-throughput

0.479

High

749968

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

1043314

CUL4A
Cullin-4A

1

3

High-throughput

0.479

High

1045567

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

5

High-throughput

0.479

High

1199151

LDB1
LIM domain-binding protein 1

1

4

Small-scale

0.479

High

1201944

TAXB1
Tax1-binding protein 1

1

12

High-throughput

0.479

High

1262631

LMO7
LIM domain only protein 7

1

6

High-throughput

0.479

High

1273768

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

Small-scale

0.479

High

1273976

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

Small-scale

0.479

High

1287897

REPS1
RalBP1-associated Eps domain-containing protein 1

1

3

High-throughput

0.479

High

1294787

PAWR
PRKC apoptosis WT1 regulator protein

1

1

High-throughput

0.479

High

1377023

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

4

High-throughput

0.479

High

1377021

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.460

High

168990

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.458

High

877956

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

Small-scale

0.458

High

1354302

RNF14
E3 ubiquitin-protein ligase RNF14

1

6

Small-scale

0.445

High

269502

STX11
Syntaxin-11

1

6

High-throughput

0.439

High

995312

GOGA2
Golgin subfamily A member 2

1

5

High-throughput

0.439

High

1149403

K1C40
Keratin, type I cytoskeletal 40

1

8

High-throughput

0.439

High

1156541

RINT1
RAD50-interacting protein 1

1

1

High-throughput

0.439

High

1238913

CBY2
Protein chibby homolog 2

1

1

High-throughput

0.439

High

1245816

CEP70
Centrosomal protein of 70 kDa

1

1

High-throughput

0.439

High

1296316

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

6

High-throughput

0.439

High

1356761

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.439

High

302226

AP2A2
AP-2 complex subunit alpha-2

1

6

High-throughput

0.437

High

534228

CD59
CD59 glycoprotein

1

1

High-throughput

0.437

High

599834

5NTD
5'-nucleotidase

1

1

High-throughput

0.437

High

1357067

COR1C
Coronin-1C

1

4

High-throughput

0.437

High

1150812

VASN
Vasorin

2

0

High-throughput

0.328

High

1235140

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024