HitPredict

Interactor 1: DRB1 (P01911)
HLA class II histocompatibility antigen, DRB1 beta chain (Human leukocyte antigen DRB1) (HLA-DRB1)
Gene: HLA-DRB1

Interactor 2: HLAE (P13747)
HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain E (sHLA-E)]
Gene: HLA-E

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 33961781
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I, C1-set~MHC_II_beta
Common GO terms GO:0000139 - Golgi membrane
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006955 - immune response
and 8 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 266
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024