HitPredict

Interactor 1: DRB1 (P01911)
HLA class II histocompatibility antigen, DRB1 beta chain (Human leukocyte antigen DRB1) (HLA-DRB1)
Gene: HLA-DRB1

Interactor 2: T106B (Q9NUM4)
Transmembrane protein 106B
Gene: TMEM106B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0031902 - late endosome membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 266 Hs			1 274
+	Hs
		945219 DRB3_HUMAN (1-266): 1.45e-103: 303: 89.10		T106B_HUMAN (1-274): 2.37e-168: 468: 100.00
+	Hs
		382639 DPB1_HUMAN (1-259): 1.5e-101: 298: 62.16		T106B_HUMAN (1-274): 2.37e-168: 468: 100.00
+	Hs
		382542 HLAA_HUMAN (34-256): 9.63e-95: 284: 22.12		T106B_HUMAN (1-274): 2.37e-168: 468: 100.00
+	Hs
		354985 DRB1_HUMAN (1-266): 2.01e-107: 313: 100.00		T106C_HUMAN (24-258): 1.75e-113: 328: 47.23
+	Hs
		382629 DPB1_HUMAN (1-259): 1.5e-101: 298: 62.16		T106C_HUMAN (24-258): 1.75e-113: 328: 47.23
+	Hs
		354976 DRB1_HUMAN (1-266): 2.01e-107: 313: 100.00		T106A_HUMAN (1-258): 2.72e-102: 300: 42.64
+	Hs
		355054 DQB1_HUMAN (3-255): 2.06e-96: 285: 62.85		T106C_HUMAN (24-258): 1.75e-113: 328: 47.23
+	Hs
		945211 DRB3_HUMAN (1-266): 1.45e-103: 303: 89.10		T106A_HUMAN (1-258): 2.72e-102: 300: 42.64
+	Hs
		355049 DQB1_HUMAN (3-255): 2.06e-96: 285: 62.85		T106A_HUMAN (1-258): 2.72e-102: 300: 42.64
+	Hs
		1278661 HMR1_HUMAN (38-258): 1.25e-73: 229: 25.45		T106A_HUMAN (1-258): 2.72e-102: 300: 42.64
+	Hs
		901905 B2MG_HUMAN (120-217): 1.6e-10: 58.9: 34.69		T106B_HUMAN (1-274): 2.37e-168: 468: 100.00
+	Hs
		588809 DPA1_HUMAN (126-256): 3.03e-13: 69.7: 28.89		T106C_HUMAN (24-258): 1.75e-113: 328: 47.23
+	Hs
		354757 DRA_HUMAN (117-217): 2.61e-10: 61.2: 30.69		T106C_HUMAN (24-258): 1.75e-113: 328: 47.23
+	Hs
		354878 DQA1_HUMAN (126-246): 2.52e-12: 67: 27.48		T106A_HUMAN (1-258): 2.72e-102: 300: 42.64
+	Hs
		1103655 HFE_HUMAN (58-237): 1.01e-11: 65.9: 27.03		T106A_HUMAN (1-258): 2.72e-102: 300: 42.64