HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: NHP6A (P11632)
Non-histone chromosomal protein 6A
Gene: NHP6A

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	29514976, 18448120, 16429126
Identification Methods	pull down, protein complementation assay, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 93
+	Hs
		297497 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		TOX4_HUMAN (17-89): 1.52e-29: 111: 36.99
+	Hs
		1087421 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		707756 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		918706 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		996694 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		996812 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Ce
		136643 H2B1_CAEEL (9-128): 2.33e-47: 150: 72.50		SSP1B_CAEEL (17-91): 3.98e-25: 99: 41.33
+	Hs
		241615 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		CIC_HUMAN (8-90): 1.81e-26: 103: 28.92
+	Hs
		420830 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		918316 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Ce
		136714 H2B4_CAEEL (8-128): 6.29e-47: 149: 71.90		SSP1B_CAEEL (17-91): 3.98e-25: 99: 41.33
+	Hs
		996768 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Sc
		355755 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		NHP6A_YEAST (1-93): 4.36e-28: 98.8: 100.00
+	Sc
		355756 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		NHP6B_YEAST (2-93): 1.18e-25: 92.8: 86.96
+	Hs
		175767 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		HMGB3_HUMAN (8-90): 1.93e-23: 90.1: 45.78
+	Sc
		355314 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		NHP6B_YEAST (2-93): 1.18e-25: 92.8: 86.96
+	Hs
		449786 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		HMGB1_HUMAN (15-88): 6.83e-10: 55.1: 38.16
+	Hs
		643380 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		HMGB2_HUMAN (15-88): 5.31e-09: 52.4: 36.84
+	Hs
		643248 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		HMGB2_HUMAN (15-88): 5.31e-09: 52.4: 36.84
+	Hs
		643302 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		HMGB2_HUMAN (15-88): 5.31e-09: 52.4: 36.84