HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: ARP4 (P80428)
Actin-related protein 4 (Actin-like protein ARP4) (Actin-like protein 4)
Gene: ARP4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	10436015, 37968396, 21179020
Identification Methods	two hybrid, far western blotting, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 489
+	Sc
		355972 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		ARP4_YEAST (1-489): 3.22e-156: 454: 100.00
+	Hs
		918457 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		POTEE_HUMAN (7-488): 7.37e-140: 430: 20.95
+	Sc
		355587 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		ACT_YEAST (301-488): 9.89e-73: 236: 27.51
+	Hs
		915467 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		ACTA_HUMAN (274-488): 3.06e-64: 214: 23.87
+	Hs
		241497 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		ACTC_HUMAN (274-488): 2.45e-64: 214: 23.87
+	Sc
		356051 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		ARP7_YEAST (17-482): 1.62e-22: 102: 23.35
+	Hs
		331522 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67
+	Hs
		331448 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67
+	Hs
		331485 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67
+	Hs
		296439 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		ACL6B_HUMAN (295-482): 7.98e-22: 99.4: 32.67
+	Sc
		355700 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		ARP7_YEAST (17-482): 1.62e-22: 102: 23.35
+	Hs
		331545 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67
+	Hs
		296461 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		ACL6B_HUMAN (295-482): 7.98e-22: 99.4: 32.67
+	Hs
		331569 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67
+	Hs
		296473 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		ACL6B_HUMAN (295-482): 7.98e-22: 99.4: 32.67