Protein: DPO5
rDNA transcriptional regulator POL5 (EC 2.7.7.7) (DNA polymerase V) (POL V) (DNA polymerase phi)

Gene: DPO5, POL5
Organism: Saccharomyces cerevisiae S288C
Interactions: 88
UniProt ID: P39985

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000166 - nucleotide binding
GO:0000182 - rDNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

816158

UTP10
U3 small nucleolar RNA-associated protein 10

4

0

High-throughput

0.658

High

637224

PWP1
Periodic tryptophan protein 1

2

5

High-throughput

0.621

High

816181

UTP4
U3 small nucleolar RNA-associated protein 4

2

2

High-throughput

0.621

High

677408

KRR1
KRR1 small subunit processome component

2

1

High-throughput

0.614

High

816165

UTP8
U3 small nucleolar RNA-associated protein 8

2

0

High-throughput

0.585

High

806524

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.576

High

524046

HSP71
Heat shock protein SSA1

3

2

High-throughput

0.569

High

816155

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

816154

UTP7
U3 small nucleolar RNA-associated protein 7

1

1

High-throughput

0.536

High

816177

PUF6
Pumilio homology domain family member 6

1

1

High-throughput

0.536

High

816171

UTP17
NET1-associated nuclear protein 1

1

2

High-throughput

0.515

High

816176

UTP15
U3 small nucleolar RNA-associated protein 15

1

4

High-throughput

0.515

High

816186

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.515

High

448173

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

816183

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

762969

SPT7
SAGA complex subunit SPT7

1

6

High-throughput

0.489

High

793926

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

4

High-throughput

0.489

High

816168

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

1

High-throughput

0.489

High

816172

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

2

High-throughput

0.489

High

816174

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.489

High

410154

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

441927

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

512459

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

670747

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

689044

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

793480

MAK5
ATP-dependent RNA helicase MAK5

1

2

High-throughput

0.479

High

816161

TRF5
Poly(A) RNA polymerase protein 1

1

1

Small-scale

0.479

High

816164

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

816166

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

High-throughput

0.479

High

816173

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

816175

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

149784

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

672890

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

674646

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

689478

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

816156

AIR1
Protein AIR1

1

0

Small-scale

0.458

High

816162

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

816170

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

816188

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

382119

H4
Histone H4

1

1

High-throughput

0.445

High

544983

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

816160

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

2

High-throughput

0.445

High

433661

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

436425

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.437

High

455082

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

504231

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

513026

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

792066

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.437

High

816167

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.437

High

816169

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

816185

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

392783

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.407

High

510526

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.407

High

526774

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

579450

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.407

High

676025

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.407

High

727052

HS104
Heat shock protein 104

1

1

High-throughput

0.407

High

741640

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.407

High

752297

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

779540

LHS1
Heat shock protein 70 homolog LHS1

1

3

High-throughput

0.407

High

816159

ERJ5
ER-localized J domain-containing protein 5

1

2

High-throughput

0.407

High

816180

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

4

High-throughput

0.407

High

721965

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

735262

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.279

Low

750590

UBC6
Ubiquitin-conjugating enzyme E2 6

1

0

High-throughput

0.279

Low

454580

TFS2
Transcription elongation factor S-II

1

0

High-throughput

0.269

Low

383719

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

435118

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

503063

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

514654

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

649497

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.249

Low

707182

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

734995

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

747385

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

753390

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

778348

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

802195

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812323

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

816157

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

816163

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

816182

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

816184

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

816187

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.249

Low

816189

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

807224

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

811092

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

816178

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

816179

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025