HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: UBP3 (Q01477)
Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)
Gene: UBP3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20508643
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 912
+	Sc
		355977 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP3_YEAST (1-912): 0: 747: 100.00
+	Hs
		707745 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP44_HUMAN (232-911): 1.26e-90: 304: 15.30
+	Hs
		271037 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP2_HUMAN (200-909): 1.81e-91: 303: 16.28
+	Hs
		1087213 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP49_HUMAN (245-912): 1.6e-86: 293: 14.71
+	Hs
		777048 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP8_HUMAN (189-909): 7.56e-80: 282: 16.51
+	Hs
		707785 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP21_HUMAN (247-909): 1.96e-80: 273: 15.69
+	Hs
		241667 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		UBP16_HUMAN (232-910): 1.38e-76: 268: 13.48
+	Hs
		707805 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP16_HUMAN (232-910): 1.38e-76: 268: 13.48
+	Hs
		918798 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		UBP16_HUMAN (232-910): 1.38e-76: 268: 13.48
+	Sc
		355960 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP10_YEAST (135-910): 3.35e-75: 264: 13.89
+	Hs
		1087499 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP20_HUMAN (409-912): 3.57e-73: 261: 15.50
+	Sc
		355576 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		UBP10_YEAST (135-910): 3.35e-75: 264: 13.89
+	Sc
		355943 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP8_YEAST (589-911): 5.51e-73: 249: 19.82
+	Sc
		355547 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		UBP8_YEAST (589-911): 5.51e-73: 249: 19.82
+	Hs
		1087318 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP7_HUMAN (524-912): 8.9e-66: 241: 16.91
+	Hs
		707688 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP38_HUMAN (412-911): 1.04e-65: 241: 13.84
+	Hs
		707705 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP7_HUMAN (524-912): 8.9e-66: 241: 16.91
+	Hs
		1231220 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		UBP7_HUMAN (524-912): 8.9e-66: 241: 16.91
+	Hs
		707807 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP3_HUMAN (428-908): 2.58e-64: 227: 16.63
+	Hs
		918801 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		UBP3_HUMAN (428-908): 2.58e-64: 227: 16.63