HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: SPP1 (Q03012)
COMPASS component SPP1 (Complex proteins associated with SET1 protein SPP1) (Set1C component SPP1) (Suppressor of PRP protein 1)
Gene: SPP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20439497
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 353
+	Hs
		1087486 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Hs
		1087376 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		241628 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		707733 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		918650 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		256413 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Hs
		256396 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Sc
		355868 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		SET3_YEAST (4-140): 3.01e-27: 114: 19.05
+	Hs
		918742 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		CXXC1_HUMAN (8-124): 2.09e-26: 112: 23.53
+	Hs
		1017308 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		1017333 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		918323 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		1087303 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PHF3_HUMAN (24-156): 4.18e-21: 96.8: 18.31
+	Hs
		241598 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		PHF3_HUMAN (24-156): 4.18e-21: 96.8: 18.31
+	Hs
		918567 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		PHF3_HUMAN (24-156): 4.18e-21: 96.8: 18.31
+	Zm
		17621 B4FYZ0_MAIZE (3-128): 6.5e-46: 147: 60.32		A0A1D6GXC6_MAIZE (18-130): 9.14e-20: 92.9: 21.85
+	Hs
		617988 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		1087485 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		918734 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		ING3_HUMAN (10-79): 1.14e-18: 88.3: 35.62
+	Hs
		1307100 H2B1N_HUMAN (7-128): 2.08e-45: 145: 70.16		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39