HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: PC (P26017)
Polycomb group protein Pc (Protein polycomb)
Gene: PC

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.725

Property	Details
Experiments	12408863, 23320494, 12351676, 17210640, 12897054, unassigned4
Identification Methods	affinity chromatography technology, far western blotting, fluorescence polarization spectroscopy, x-ray crystallography, experimental interaction detection
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 390
+	Hs
		316000 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX6_HUMAN (17-378): 1.71e-66: 218: 20.46
+	Hs
		316040 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX6_HUMAN (17-378): 1.71e-66: 218: 20.46
+	Hs
		935259 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX8_HUMAN (17-380): 4.11e-60: 201: 20.15
+	Hs
		935387 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL_HUMAN (5-282): 8.67e-54: 189: 15.73
+	Hs
		123231 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX4_HUMAN (17-338): 4.27e-46: 167: 18.53
+	Hs
		123254 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX4_HUMAN (17-338): 4.27e-46: 167: 18.53
+	Hs
		934987 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL2_HUMAN (24-218): 8.03e-41: 152: 16.74
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (24-166): 2.55e-41: 152: 19.18
+	Hs
		934768 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX2_HUMAN (16-333): 1.47e-38: 146: 16.52
+	Hs
		327837 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX7_HUMAN (17-237): 2.26e-39: 142: 20.18
+	Hs
		327844 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX7_HUMAN (17-237): 2.26e-39: 142: 20.18
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (26-165): 4.77e-32: 127: 13.99
+	Hs
		935156 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		MPP8_HUMAN (18-333): 1.86e-27: 116: 12.97
+	Hs
		934721 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX3_HUMAN (6-87): 1.19e-28: 112: 30.49
+	Hs
		1027017 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX3_HUMAN (6-87): 1.19e-28: 112: 30.49
+	Hs
		800341 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX5_HUMAN (7-124): 8.38e-26: 104: 23.73
+	Hs
		800397 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX5_HUMAN (7-124): 8.38e-26: 104: 23.73
+	Hs
		934657 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX1_HUMAN (32-120): 1.61e-23: 98.5: 31.46
+	Mm
		935445 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		CBX1_MOUSE (32-120): 1.61e-23: 98.5: 31.46
+	Hs
		949795 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX1_HUMAN (32-120): 1.61e-23: 98.5: 31.46