HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: BTAF1 (P32333)
TATA-binding protein-associated factor MOT1 (TBP-associated factor MOT1) (EC 3.6.4.-) (Modifier of transcription 1)
Gene: MOT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	16429126, 18596064, 22199229, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 1867
+	Hs
		917635 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD6_HUMAN (989-1867): 0: 703: 21.90
+	Hs
		918062 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD7_HUMAN (1032-1867): 0: 639: 22.71
+	Hs
		917965 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD8_HUMAN (999-1867): 0: 626: 20.61
+	Hs
		917364 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD9_HUMAN (1006-1867): 0: 613: 22.54
+	Hs
		917277 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD4_HUMAN (1202-1853): 0: 611: 27.31
+	Sp
		144535 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		HRP3_SCHPO (1073-1863): 0: 608: 23.06
+	Sc
		356424 H4_YEAST (1-103): 5.28e-47: 147: 100.00		ISW1_YEAST (1226-1864): 0: 594: 28.40
+	Hs
		917182 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD3_HUMAN (1190-1853): 0: 605: 26.64
+	Hs
		229352 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMCA5_HUMAN (1154-1862): 0: 603: 26.69
+	Sc
		356350 H4_YEAST (1-103): 5.28e-47: 147: 100.00		CHD1_YEAST (1071-1863): 0: 589: 23.01
+	Sc
		356774 H4_YEAST (1-103): 5.28e-47: 147: 100.00		ISW2_YEAST (1159-1853): 0: 589: 27.42
+	Hs
		846914 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMCA4_HUMAN (1203-1863): 0: 601: 27.48
+	Dm
		950383 H4_DROME (18-103): 2.42e-41: 133: 90.70		ISWI_DROME (1161-1843): 0: 587: 27.26
+	Hs
		918003 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HELLS_HUMAN (1194-1856): 0: 572: 25.61
+	Hs
		917147 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ERCC6_HUMAN (1262-1811): 1.16e-80: 296: 35.56
+	Sc
		356248 H4_YEAST (1-103): 5.28e-47: 147: 100.00		SNF2_YEAST (1266-1781): 1.58e-75: 281: 34.93
+	Sc
		356344 H4_YEAST (1-103): 5.28e-47: 147: 100.00		STH1_YEAST (1240-1781): 8.75e-76: 280: 35.28