HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: RPD3 (P32561)
Histone deacetylase RPD3 (EC 3.5.1.98) (Transcriptional regulatory protein RPD3)
Gene: RPD3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22199229
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 433
+	Mm
		140249 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		HDAC1_MOUSE (15-428): 0: 598: 61.11
+	Hs
		917226 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC1_HUMAN (15-428): 0: 598: 60.87
+	Dm
		950398 H4_DROME (18-103): 2.42e-41: 133: 90.70		HDAC1_DROME (15-432): 0: 586: 59.57
+	Hs
		917682 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC2_HUMAN (18-432): 0: 583: 61.69
+	Mm
		918237 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		HDAC2_MOUSE (18-432): 0: 581: 61.45
+	At
		886854 H4_ARATH (18-103): 5.22e-41: 132: 89.54		HDA6_ARATH (1-431): 0: 543: 55.43
+	Hs
		177252 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC3_HUMAN (19-433): 0: 534: 57.31
+	Sp
		140573 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60
+	Sc
		356604 H4_YEAST (1-103): 5.28e-47: 147: 100.00		HOS2_YEAST (3-430): 3.66e-168: 481: 45.04
+	Hs
		917872 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC8_HUMAN (5-383): 3.01e-144: 417: 40.26
+	Hs
		880666 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC4_HUMAN (1-418): 7.15e-130: 402: 22.96
+	Sc
		356643 H4_YEAST (1-103): 5.28e-47: 147: 100.00		HDA1_YEAST (8-340): 3.39e-120: 367: 25.21
+	Hs
		918077 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC6_HUMAN (21-331): 1.58e-90: 299: 23.84