HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

The method score is based on:

Property	Details
Experiments	29326975, 27684187, 33431799
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0000209 - protein polyubiquitination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 7 others more... GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0019900 - kinase binding GO:0030018 - Z disc GO:0031625 - ubiquitin protein ligase binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0046332 - SMAD binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	781
Hs

1	303

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024