HitPredict

Interactor 1: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Interactor 2: B2CL1 (Q64373)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: Bcl2l1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 30683842, 14963330, 16151013
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~P53, BH4~P53
Common GO terms GO:0001701 - in utero embryonic development
GO:0001836 - release of cytochrome c from mitochondria
GO:0002931 - response to ischemia
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
and 12 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 390
Mm

1 233
+ Hs
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024