Protein: NFM
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)

Gene: NFM, NEFM
Organism: Homo sapiens
Interactions: 185
UniProt ID: P07197

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005737 - cytoplasm
GO:0005882 - intermediate filament
GO:0005883 - neurofilament
GO:0008017 - microtubule binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

422326

VIME
Vimentin

8

20

High-throughput

0.971

High

422125

NFL
Neurofilament light polypeptide

7

20

High-throughput

0.962

High

422365

NEST
Nestin

3

20

High-throughput

0.861

High

422405

AINX
Alpha-internexin

3

20

High-throughput

0.861

High

422335

NFH
Neurofilament heavy polypeptide

2

20

High-throughput

0.811

High

422337

GFAP
Glial fibrillary acidic protein

2

20

High-throughput

0.811

High

422344

DESM
Desmin

2

20

High-throughput

0.811

High

422457

SYNCI
Syncoilin

2

20

High-throughput

0.811

High

280846

KRT37
Keratin, type I cuticular Ha7

1

20

High-throughput

0.691

High

280944

KRT38
Keratin, type I cuticular Ha8

1

20

High-throughput

0.691

High

359292

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.691

High

422328

K2C7
Keratin, type II cytoskeletal 7

1

20

High-throughput

0.691

High

422329

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.691

High

422393

K1H2
Keratin, type I cuticular Ha2

1

20

High-throughput

0.691

High

422399

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.691

High

422411

K1C39
Keratin, type I cytoskeletal 39

1

20

High-throughput

0.691

High

422415

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.691

High

422420

KT222
Keratin-like protein KRT222

1

20

High-throughput

0.691

High

422398

PLEC
Plectin

3

20

High-throughput

0.667

High

422406

KIF7
Kinesin-like protein KIF7

3

5

High-throughput

0.667

High

422455

GAN
Gigaxonin

3

17

High-throughput

0.667

High

422324

CAN1
Calpain-1 catalytic subunit

2

7

High-throughput

0.628

High

422386

GOGA2
Golgin subfamily A member 2

2

20

High-throughput

0.628

High

422438

RSPRY
RING finger and SPRY domain-containing protein 1

2

10

High-throughput

0.628

High

213925

KRT86
Keratin, type II cuticular Hb6

1

20

High-throughput

0.618

High

408710

K1C18
Keratin, type I cytoskeletal 18

1

20

High-throughput

0.618

High

408975

K2C8
Keratin, type II cytoskeletal 8

1

20

High-throughput

0.618

High

422327

K1C19
Keratin, type I cytoskeletal 19

1

20

High-throughput

0.618

High

422387

MYO9B
Unconventional myosin-IXb

2

15

High-throughput

0.611

High

422418

LUR1L
Leucine rich adaptor protein 1-like

3

2

High-throughput

0.609

High

422435

FBXW5
F-box/WD repeat-containing protein 5

2

0

High-throughput

0.602

High

422469

TNIK
TRAF2 and NCK-interacting protein kinase

2

17

High-throughput

0.590

High

422462

DISC1
Disrupted in schizophrenia 1 protein

2

2

High-throughput

0.576

High

422369

AF17
Protein AF-17

2

3

High-throughput

0.574

High

422384

CALD1
Caldesmon

2

20

High-throughput

0.574

High

422440

CC120
Coiled-coil domain-containing protein 120

2

5

High-throughput

0.574

High

422442

F167A
Protein FAM167A

2

1

High-throughput

0.574

High

422403

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.561

High

234362

EVI5
Ecotropic viral integration site 5 protein homolog

2

3

High-throughput

0.558

High

422474

CRBG1
Beta/gamma crystallin domain-containing protein 1

2

15

High-throughput

0.558

High

234464

DSCAM
Cell adhesion molecule DSCAM

1

6

High-throughput

0.541

High

422404

ITSN1
Intersectin-1

1

20

High-throughput

0.541

High

59088

VWA8
von Willebrand factor A domain-containing protein 8

1

1

High-throughput

0.536

High

243258

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.536

High

422339

IDE
Insulin-degrading enzyme

1

12

High-throughput

0.536

High

422349

S100P
Protein S100-P

1

16

High-throughput

0.536

High

422357

NUP62
Nuclear pore glycoprotein p62

1

5

High-throughput

0.536

High

422360

HD
Huntingtin

1

11

High-throughput

0.536

High

422370

EPIPL
Epiplakin

1

20

High-throughput

0.536

High

422375

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.536

High

422383

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

2

High-throughput

0.536

High

422388

SQSTM
Sequestosome-1

1

7

High-throughput

0.536

High

422391

MAP7
Ensconsin

1

20

High-throughput

0.536

High

422392

SRC8
Src substrate cortactin

1

20

High-throughput

0.536

High

422410

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

20

High-throughput

0.536

High

422475

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.536

High

422338

DRD2
D(2) dopamine receptor

1

2

Small-scale

0.527

High

401270

JUN
Transcription factor Jun

2

16

High-throughput

0.521

High

422333

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.515

High

345284

FOS
Protein c-Fos

1

13

High-throughput

0.512

High

422325

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

10

High-throughput

0.489

High

422364

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.489

High

422377

HBB
Hemoglobin subunit beta

1

4

High-throughput

0.489

High

422381

LAT1
Large neutral amino acids transporter small subunit 1

1

1

High-throughput

0.489

High

422396

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

13

High-throughput

0.489

High

422400

SSXT
Protein SSXT

1

1

High-throughput

0.489

High

422402

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.489

High

422407

CF184
Cilia- and flagella-associated protein 184

1

2

High-throughput

0.489

High

422419

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

422426

CCHCR
Coiled-coil alpha-helical rod protein 1

1

20

High-throughput

0.489

High

422432

YLAT2
Y+L amino acid transporter 2

1

1

High-throughput

0.489

High

422459

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

1

High-throughput

0.489

High

422468

STML2
Stomatin-like protein 2, mitochondrial

1

2

High-throughput

0.489

High

361426

APOE
Apolipoprotein E

1

0

Small-scale

0.480

High

161291

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

14

High-throughput

0.479

High

207876

XPOT
Exportin-T

1

6

High-throughput

0.479

High

226277

PRKN
E3 ubiquitin-protein ligase parkin

1

19

High-throughput

0.479

High

242652

IF2P
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.479

High

307938

ZWINT
ZW10 interactor

1

2

High-throughput

0.479

High

308323

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

345705

MYC
Myc proto-oncogene protein

1

19

High-throughput

0.479

High

403057

LA
Lupus La protein

1

13

High-throughput

0.479

High

422334

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.479

High

422340

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

422341

ETS1
Protein C-ets-1

1

2

High-throughput

0.479

High

422342

DESP
Desmoplakin

1

20

High-throughput

0.479

High

422343

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

18

High-throughput

0.479

High

422345

RL7
Large ribosomal subunit protein uL30

1

1

High-throughput

0.479

High

422346

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

9

High-throughput

0.479

High

422350

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.479

High

422355

MYH9
Myosin-9

1

11

High-throughput

0.479

High

422356

MYH10
Myosin-10

1

11

High-throughput

0.479

High

422358

SYUA
Alpha-synuclein

1

5

High-throughput

0.479

High

422361

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

20

High-throughput

0.479

High

422362

MAP1B
Microtubule-associated protein 1B

1

16

High-throughput

0.479

High

422363

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

422366

MCM2
DNA replication licensing factor MCM2

1

11

High-throughput

0.479

High

422367

R144A
E3 ubiquitin-protein ligase RNF144A

1

5

Small-scale

0.479

High

422368

PLK1
Serine/threonine-protein kinase PLK1

1

5

High-throughput

0.479

High

422372

PRS8
26S proteasome regulatory subunit 8

1

4

High-throughput

0.479

High

422385

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.479

High

422389

HDAC1
Histone deacetylase 1

1

19

High-throughput

0.479

High

422394

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

1

1

Small-scale

0.479

High

422397

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

422408

MIDN
Midnolin

1

5

High-throughput

0.479

High

422416

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

20

High-throughput

0.479

High

422417

LRC49
Leucine-rich repeat-containing protein 49

1

12

High-throughput

0.479

High

422424

SYNE1
Nesprin-1

1

18

High-throughput

0.479

High

422425

BICD2
Protein bicaudal D homolog 2

1

20

High-throughput

0.479

High

422427

DLG5
Disks large homolog 5

1

9

High-throughput

0.479

High

422429

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.479

High

422430

SSH1
Protein phosphatase Slingshot homolog 1

1

5

High-throughput

0.479

High

422433

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

15

High-throughput

0.479

High

422444

NEB2
Neurabin-2

1

20

High-throughput

0.479

High

422445

ANM1
Protein arginine N-methyltransferase 1

1

11

High-throughput

0.479

High

422450

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.479

High

422452

REN3B
Regulator of nonsense transcripts 3B

1

4

High-throughput

0.479

High

422453

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

422456

SENP3
Sentrin-specific protease 3

1

3

High-throughput

0.479

High

422458

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

4

High-throughput

0.479

High

422461

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.479

High

422464

STK26
Serine/threonine-protein kinase 26

1

20

High-throughput

0.479

High

69717

FHAD1
Forkhead-associated domain-containing protein 1

1

12

High-throughput

0.470

High

422348

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

422351

CALR
Calreticulin

1

0

High-throughput

0.458

High

422373

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

422379

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

422413

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.458

High

422447

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.458

High

239714

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.445

High

422330

CALM3
Calmodulin-3

1

2

High-throughput

0.445

High

422331

SCHI1
Schwannomin-interacting protein 1

1

1

High-throughput

0.445

High

422332

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.445

High

422380

ANK2
Ankyrin-2

1

15

High-throughput

0.445

High

148292

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.437

High

165377

SR140
U2 snRNP-associated SURP motif-containing protein

1

1

High-throughput

0.437

High

231970

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.437

High

378911

MYCN
N-myc proto-oncogene protein

1

19

High-throughput

0.437

High

422336

ADT1
ADP/ATP translocase 1

1

2

High-throughput

0.437

High

422347

GCSP
Glycine dehydrogenase

1

3

High-throughput

0.437

High

422354

MCM7
DNA replication licensing factor MCM7

1

11

High-throughput

0.437

High

422359

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

422371

RAC3
Ras-related C3 botulinum toxin substrate 3

1

4

High-throughput

0.437

High

422376

H2B1C
Histone H2B type 1-C/E/F/G/I

1

12

High-throughput

0.437

High

422378

PSG9
Pregnancy-specific beta-1-glycoprotein 9

1

2

High-throughput

0.437

High

422382

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

4

High-throughput

0.437

High

422390

CUL4B
Cullin-4B

1

20

High-throughput

0.437

High

422395

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

422401

PCH2
Pachytene checkpoint protein 2 homolog

1

8

High-throughput

0.437

High

422412

FA83H
Protein FAM83H

1

10

High-throughput

0.437

High

422414

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

5

High-throughput

0.437

High

422428

ATX2L
Ataxin-2-like protein

1

2

High-throughput

0.437

High

422431

TITIN
Titin

1

19

High-throughput

0.437

High

422434

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.437

High

422436

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.437

High

422437

PF21A
PHD finger protein 21A

1

20

High-throughput

0.437

High

422439

SPDLY
Protein Spindly

1

20

High-throughput

0.437

High

422446

MICU1
Calcium uptake protein 1, mitochondrial

1

4

High-throughput

0.437

High

422448

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.437

High

422451

FACD2
Fanconi anemia group D2 protein

1

19

High-throughput

0.437

High

422460

ANM8
Protein arginine N-methyltransferase 8

1

11

High-throughput

0.437

High

422463

DYH9
Dynein axonemal heavy chain 9

1

1

High-throughput

0.437

High

422465

DIC
Mitochondrial dicarboxylate carrier

1

4

High-throughput

0.437

High

422466

CCD39
Coiled-coil domain-containing protein 39

1

20

High-throughput

0.437

High

422467

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

2

High-throughput

0.437

High

422470

RCOR1
REST corepressor 1

1

6

High-throughput

0.437

High

422472

AP3M1
AP-3 complex subunit mu-1

1

10

High-throughput

0.437

High

422473

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

1

10

High-throughput

0.437

High

422476

SETBP
SET-binding protein

1

1

High-throughput

0.437

High

320949

PTBP3
Polypyrimidine tract-binding protein 3

1

3

High-throughput

0.407

High

353614

IGHG1
Immunoglobulin heavy constant gamma 1

1

6

High-throughput

0.407

High

422422

POC5
Centrosomal protein POC5

1

4

High-throughput

0.407

High

422423

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.407

High

422443

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.407

High

422471

ITM2B
Integral membrane protein 2B

1

16

High-throughput

0.407

High

422449

CC106
Coiled-coil domain-containing protein 106

3

0

High-throughput

0.347

High

414128

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.301

High

422454

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.279

Low

237012

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.249

Low

422352

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.249

Low

422353

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.249

Low

422374

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.249

Low

422409

NU188
Nucleoporin NUP188

1

0

High-throughput

0.249

Low

422421

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.249

Low

422441

MRP9
ATP-binding cassette sub-family C member 12

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024