Protein: SHOC2
Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)

Gene: SHOC2
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9UQ13

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

906202

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

6

16

High-throughput

0.732

High

738129

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

5

16

High-throughput

0.716

High

1301465

ERBIN
Erbin

1

19

Small-scale

0.715

High

375101

RAF1
RAF proto-oncogene serine/threonine-protein kinase

4

20

Small-scale

0.683

High

349737

RASH
GTPase HRas

3

16

Small-scale

0.680

High

1192270

HUWE1
E3 ubiquitin-protein ligase HUWE1

3

2

Small-scale

0.669

High

382564

HLAA
HLA class I histocompatibility antigen, A alpha chain

2

2

High-throughput

0.659

High

488423

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

2

High-throughput

0.659

High

1357815

SHOC2
Leucine-rich repeat protein SHOC-2

1

19

High-throughput

0.618

High

350693

RASK
GTPase KRas

2

17

Small-scale

0.600

High

156102

RASM
Ras-related protein M-Ras

2

9

Small-scale

0.584

High

276676

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

2

1

High-throughput

0.571

High

340552

PGK1
Phosphoglycerate kinase 1

2

1

High-throughput

0.571

High

376341

ANXA1
Annexin A1

2

1

High-throughput

0.571

High

388803

HSPB1
Heat shock protein beta-1

2

1

High-throughput

0.571

High

436120

ANXA6
Annexin A6

2

1

High-throughput

0.571

High

438999

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

2

1

High-throughput

0.571

High

457169

ALDOC
Fructose-bisphosphate aldolase C

2

1

High-throughput

0.571

High

532652

TCTP
Translationally-controlled tumor protein

2

1

High-throughput

0.571

High

542479

PLAK
Junction plakoglobin

2

9

High-throughput

0.571

High

670867

PRDX5
Peroxiredoxin-5, mitochondrial

2

1

High-throughput

0.571

High

683820

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.571

High

893508

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

1

High-throughput

0.571

High

910166

1433E
14-3-3 protein epsilon

2

8

High-throughput

0.571

High

1037439

TBB3
Tubulin beta-3 chain

2

2

High-throughput

0.571

High

1357816

SGT1
Protein SGT1 homolog

2

18

High-throughput

0.571

High

1273970

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

Small-scale

0.561

High

1281479

FBXW7
F-box/WD repeat-containing protein 7

1

7

Small-scale

0.561

High

907187

PRS8
26S proteasome regulatory subunit 8

1

0

Small-scale

0.549

High

337039

PNPH
Purine nucleoside phosphorylase

2

0

High-throughput

0.547

High

509276

G6PD
Glucose-6-phosphate 1-dehydrogenase

2

0

High-throughput

0.547

High

682534

PUR9
Bifunctional purine biosynthesis protein ATIC

2

0

High-throughput

0.547

High

827652

EFTU
Elongation factor Tu, mitochondrial

2

0

High-throughput

0.547

High

981105

LGUL
Lactoylglutathione lyase

2

0

High-throughput

0.547

High

1077174

MARE1
Microtubule-associated protein RP/EB family member 1

2

0

High-throughput

0.547

High

1345762

OLA1
Obg-like ATPase 1

2

0

High-throughput

0.547

High

348256

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.536

High

393832

ALDOB
Fructose-bisphosphate aldolase B

1

1

High-throughput

0.536

High

801467

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

906638

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

16

High-throughput

0.536

High

1039947

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.536

High

1344843

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.536

High

398972

HMGN2
Non-histone chromosomal protein HMG-17

1

1

High-throughput

0.515

High

175307

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

396062

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

370727

ESR1
Estrogen receptor

1

12

High-throughput

0.500

High

560011

H12
Histone H1.2

1

0

High-throughput

0.493

High

883063

H2BFS
Histone H2B type F-S

1

0

High-throughput

0.493

High

1231989

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

1

High-throughput

0.489

High

73193

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

10

High-throughput

0.479

High

537133

TRI27
Zinc finger protein RFP

1

4

Small-scale

0.479

High

787603

MTOR
Serine/threonine-protein kinase mTOR

1

3

Small-scale

0.479

High

905408

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

2

Small-scale

0.479

High

999220

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

1087852

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

2

High-throughput

0.479

High

1172297

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1230069

RPTOR
Regulatory-associated protein of mTOR

1

6

Small-scale

0.479

High

1269946

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

1287433

OPTN
Optineurin

1

7

High-throughput

0.479

High

1357732

PLCL2
Inactive phospholipase C-like protein 2

1

2

High-throughput

0.479

High

875440

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

497816

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

1235468

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

5

Small-scale

0.437

High

337264

AATM
Aspartate aminotransferase, mitochondrial

2

0

High-throughput

0.298

High

1349794

TM14C
Transmembrane protein 14C

2

0

High-throughput

0.298

High

1261175

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024