HitPredict

Interactor 1: K1C14 (P02533)
Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)
Gene: KRT14

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 472 Hs			1 334
+	Hs
		531502 K1C13_HUMAN (109-439): 2.66e-153: 445: 71.99		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		445097 K1C16_HUMAN (1-441): 3.53e-146: 427: 84.42		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		980302 K1C17_HUMAN (108-470): 1.08e-144: 422: 82.37		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		531404 K1C10_HUMAN (110-420): 1.2e-131: 394: 69.43		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		318857 K2C75_HUMAN (3-437): 1.6e-87: 279: 27.46		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		1110343 K2C71_HUMAN (5-429): 3.56e-83: 267: 24.82		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		124736 K1C16_HUMAN (1-441): 3.53e-146: 427: 84.42		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		380507 K2C6B_HUMAN (23-445): 5.12e-76: 250: 24.94		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		821681 K2C6C_HUMAN (23-445): 1.16e-75: 249: 25.18		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		359521 K2C6A_HUMAN (23-445): 8.97e-75: 247: 25.18		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		531613 K2C5_HUMAN (80-429): 1.41e-74: 247: 26.99		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		124748 K1C10_HUMAN (110-420): 1.2e-131: 394: 69.43		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		124710 K1C14_HUMAN (1-472): 9.98e-121: 362: 100.00		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		177055 K2C73_HUMAN (2-429): 6.97e-95: 298: 26.28		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57
+	Hs
		124717 K2C6B_HUMAN (23-445): 5.12e-76: 250: 24.94		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		124797 K2C6C_HUMAN (23-445): 1.16e-75: 249: 25.18		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		124711 K2C6A_HUMAN (23-445): 8.97e-75: 247: 25.18		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48