Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: LMNB2 (Q03252)
Lamin-B2
Gene: LMNB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 24981860, 26186194, 24623722, 29568061, 30021884, 34079125, 33961781, 35271311, 32344865, 37071682, 22412018, 21346760, unassigned1655
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament, LTD~LTD
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005635 - nuclear envelope
GO:0005652 - nuclear lamina
GO:0005882 - intermediate filament
GO:0006998 - nuclear envelope organization
and 5 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 664
Hs

1 620
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024