HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: ELYS (Q8WYP5)
Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1)
Gene: AHCTF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	24927568, 29568061, 34079125, 32344865, 22412018
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016363 - nuclear matrix and 1 others more... GO:0031965 - nuclear membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 2266
+	Hs
		595335 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		ELYS_HUMAN (1-2266): 0: 1829: 100.00
+	Hs
		443696 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ELYS_HUMAN (1-2266): 0: 1829: 100.00
+	Hs
		359942 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MDC1_HUMAN (1007-2265): 2.16e-22: 108: 7.77
+	Hs
		360224 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TITIN_HUMAN (1410-2266): 1.29e-14: 83: 8.21
+	Hs
		359745 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MAP1B_HUMAN (1369-2261): 2.54e-09: 65.2: 8.14
+	Hs
		443464 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ANK2_HUMAN (917-2220): 5.27e-46: 186: 11.46
+	Hs
		422166 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ANK2_HUMAN (917-2220): 5.27e-46: 186: 11.46
+	Ce
		1090116 LMN1_CAEEL (1-539): 1.07e-53: 195: 29.49		MEL28_CAEEL (1449-2255): 1.48e-16: 89: 10.84
+	Hs
		443800 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		TARA_HUMAN (961-2134): 2.5e-15: 84.9: 7.53
+	Hs
		443385 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		MAP1B_HUMAN (1369-2261): 2.54e-09: 65.2: 8.14