HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 626
+	Hs
		595420 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		443815 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		380457 K2C6B_HUMAN (24-407): 5.03e-115: 357: 23.51		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		360242 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		380511 K2C6B_HUMAN (24-407): 5.03e-115: 357: 23.51		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		360257 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		1205247 K2C73_HUMAN (23-390): 1.74e-50: 185: 23.85		POC1A_HUMAN (391-623): 1.51e-49: 179: 12.45
+	Hs
		359881 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		903150 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		595176 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		535382 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ERCC8_HUMAN (305-532): 1.35e-57: 200: 19.92
+	Hs
		595354 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		535516 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83