Interactor 1: HPRT (P00492)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)
Gene: HPRT1
Interactor 2: HPRT (P00492)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)
Gene: HPRT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.918 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 25502805, 31515488, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pribosyltran~Pribosyltran |
| Common GO terms | GO:0000166 - nucleotide binding GO:0000287 - magnesium ion binding GO:0001913 - T cell mediated cytotoxicity GO:0001975 - response to amphetamine GO:0004422 - hypoxanthine phosphoribosyltransferase activity and 26 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
