Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 11478883, 1694173
Identification Methods pull down, solid phase assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_beta~fn3
Common GO terms GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007044 - cell-substrate junction assembly
and 8 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 788
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Last updated: 15 Jul 2024