Protein: AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]

Gene: AASS
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q9UDR5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0004753 - saccharopine dehydrogenase activity
GO:0004754 - saccharopine dehydrogenase (NAD+, L-lysine-forming) activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

348143

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

1051132

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

1219084

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

175280

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

228969

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

263014

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.479

High

377777

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

647356

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

683787

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.479

High

684375

1433S
14-3-3 protein sigma

1

6

High-throughput

0.479

High

777779

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

894552

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.479

High

905217

1433G
14-3-3 protein gamma

1

6

High-throughput

0.479

High

927622

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

951432

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.479

High

982587

1433F
14-3-3 protein eta

1

6

High-throughput

0.479

High

1020600

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

1202476

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.479

High

1346512

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1354482

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.479

High

440786

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

455967

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

486672

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

500186

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

525668

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

553968

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652509

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

780259

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

910123

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

981474

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1042752

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1045894

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1068114

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1075022

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

1086840

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1128284

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1172118

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1243144

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.458

High

1314229

TR61B
tRNA

1

0

High-throughput

0.458

High

1331536

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1333122

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1342881

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.458

High

1354481

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1204891

VP37D
Vacuolar protein sorting-associated protein 37D

2

0

High-throughput

0.328

High

1067642

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1233862

ARG39
Rho guanine nucleotide exchange factor 39

1

0

High-throughput

0.279

Low

1253051

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1354483

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

178030

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.249

Low

721686

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1233477

NIN
Ninein

1

0

High-throughput

0.249

Low

1302879

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

2126

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024