HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: ITIH2 (P19823)
Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23750785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005788 - endoplasmic reticulum lumen GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome GO:0072562 - blood microparticle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2477 Hs			1 946
+	Hs
		362804 FINC_HUMAN (1-2477): 0: 1538: 100.00		ITIH1_HUMAN (54-940): 0: 963: 39.11
+	Hs
		363149 FINC_HUMAN (1-2477): 0: 1538: 100.00		ITIH4_HUMAN (64-919): 0: 785: 33.23
+	Hs
		363093 FINC_HUMAN (1-2477): 0: 1538: 100.00		CO7A1_HUMAN (309-851): 9.3e-45: 178: 13.60
+	Hs
		439237 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		COEA1_HUMAN (300-490): 2.45e-32: 138: 18.37
+	Hs
		540424 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		COEA1_HUMAN (300-490): 2.45e-32: 138: 18.37
+	Hs
		984734 COKA1_HUMAN (895-1359): 3.91e-12: 74.3: 22.43		COEA1_HUMAN (300-490): 2.45e-32: 138: 18.37
+	Hs
		439253 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		COCA1_HUMAN (302-490): 7.25e-28: 124: 16.50
+	Hs
		540439 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		COCA1_HUMAN (302-490): 7.25e-28: 124: 16.50
+	Mm
		1144386 CO7A1_MOUSE (1981-2291): 4.47e-24: 114: 19.62		CO7A1_MOUSE (165-495): 1.41e-10: 68: 12.25