HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: LOXL3 (P58215)
Lysyl oxidase homolog 3 (EC 1.4.3.-) (EC 1.4.3.13) (Lysyl oxidase-like protein 3)
Gene: LOXL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	26954549
Identification Methods	oxidoreductase assay
Interaction Type	oxidoreductase activity electron transfer reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2477 Hs			1 753
+	Mm
		506798 FINC_MOUSE (1-2477): 0: 1499: 91.73		LOXL3_MOUSE (1-753): 0: 1054: 92.71
+	Hs
		363220 FINC_HUMAN (1-2477): 0: 1538: 100.00		C163A_HUMAN (21-437): 4.1e-105: 349: 31.58
+	Hs
		362851 FINC_HUMAN (1-2477): 0: 1538: 100.00		LYOX_HUMAN (525-729): 1.1e-100: 318: 51.21
+	Hs
		363106 FINC_HUMAN (1-2477): 0: 1538: 100.00		LG3BP_HUMAN (162-281): 1e-32: 136: 27.50
+	Hs
		885370 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		LOXL3_HUMAN (1-753): 0: 1048: 100.00
+	Hs
		957569 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		LOXL2_HUMAN (26-752): 0: 990: 56.19
+	Hs
		439228 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		LYOX_HUMAN (525-729): 1.1e-100: 318: 51.21
+	Hs
		657668 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		LYOX_HUMAN (525-729): 1.1e-100: 318: 51.21
+	Hs
		1295361 COCA1_HUMAN (1630-2407): 3.35e-35: 150: 12.97		HIPL1_HUMAN (160-281): 1.53e-27: 120: 24.59