Interactor 1: PLF4 (P02776)
Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into: Platelet factor 4, short form (Endothelial cell growth inhibitor)]
Gene: PF4

Interactor 2: CXCL6 (P80162)
C-X-C motif chemokine 6 (Chemokine alpha 3) (CKA-3) (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3]
Gene: CXCL6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, surface plasmon resonance, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0008009 - chemokine activity
GO:0008201 - heparin binding
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 101
Hs

1 114
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Last updated: 15 Jul 2024