HitPredict

Interactor 1: CXL10 (P02778)
C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) [Cleaved into: CXCL10(1-73)]
Gene: CXCL10

Interactor 2: DPP4 (P27487)
Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]
Gene: DPP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	18275857, 21314817
Identification Methods	enzymatic study, protease assay
Interaction Type	direct interaction, cleavage reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005576 - extracellular region GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 766
+	Hs
		150313 CXL11_HUMAN (1-94): 7.39e-27: 95.9: 30.85		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		587768 CXCL2_HUMAN (19-95): 1.75e-22: 85.5: 27.27		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		648737 CXCL9_HUMAN (20-90): 8.47e-20: 78.9: 40.85		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		648685 SDF1_HUMAN (1-95): 7.7e-20: 78.2: 25.26		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		364116 CXL10_HUMAN (1-98): 4.33e-29: 101: 100.00		DPP8_HUMAN (79-764): 1.63e-169: 513: 22.21
+	Hs
		150330 CXL11_HUMAN (1-94): 7.39e-27: 95.9: 30.85		DPP8_HUMAN (79-764): 1.63e-169: 513: 22.21
+	Hs
		816318 SDF1_HUMAN (1-95): 7.7e-20: 78.2: 25.26		DPP8_HUMAN (79-764): 1.63e-169: 513: 22.21