HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: LEU1 (P06208)
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase)
Gene: LEU4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26217697, 25452130, 31399574
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 619
+	Sc
		411210 HSC82_YEAST (1-709): 0: 973: 94.64		LEU1_YEAST (1-619): 0: 725: 100.00
+	Sc
		367062 HSP82_YEAST (1-709): 0: 984: 100.00		HOSM_YEAST (33-483): 9.5e-127: 382: 18.34
+	Sc
		544578 HSC82_YEAST (1-709): 0: 973: 94.64		HOSM_YEAST (33-483): 9.5e-127: 382: 18.34
+	Sc
		366565 HSP82_YEAST (1-709): 0: 984: 100.00		HOSC_YEAST (48-472): 7.87e-119: 361: 18.75
+	Ca
		804488 HSP90_CANAL (4-709): 0: 959: 81.75		Q59TC4_CANAL (48-486): 2.38e-126: 380: 18.08
+	Sc
		544058 HSC82_YEAST (1-709): 0: 973: 94.64		HOSC_YEAST (48-472): 7.87e-119: 361: 18.75
+	Sc
		365956 HSP82_YEAST (1-709): 0: 984: 100.00		PYC2_YEAST (14-365): 5.18e-84: 287: 13.56
+	Sc
		543369 HSC82_YEAST (1-709): 0: 973: 94.64		PYC2_YEAST (14-365): 5.18e-84: 287: 13.56