Interactor 1: HPT (P00738)
Haptoglobin (Zonulin) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain]
Gene: HP

Interactor 2: HBA (P69905)
Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin]
Gene: HBA, HBA1;

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37343697
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Globin~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0031838 - haptoglobin-hemoglobin complex
GO:0042542 - response to hydrogen peroxide
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 406
Hs

1 142
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025