HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: IMB2 (P38217)
Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)
Gene: KAP104

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	11805837, 31399574
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 918
+	Sc
		543622 HSC82_YEAST (1-709): 0: 973: 94.64		IMB2_YEAST (1-918): 0: 580: 100.00
+	Mm
		432420 HS90A_MOUSE (4-709): 0: 1012: 60.72		IMB1_MOUSE (13-885): 3.2e-96: 324: 11.87
+	Sc
		365959 HSP82_YEAST (1-709): 0: 984: 100.00		IMB3_YEAST (9-858): 2.92e-90: 311: 15.32
+	Sc
		543372 HSC82_YEAST (1-709): 0: 973: 94.64		IMB3_YEAST (9-858): 2.92e-90: 311: 15.32
+	Sc
		366915 HSP82_YEAST (1-709): 0: 984: 100.00		IMB1_YEAST (14-865): 3.48e-86: 296: 12.25
+	Sc
		544439 HSC82_YEAST (1-709): 0: 973: 94.64		IMB1_YEAST (14-865): 3.48e-86: 296: 12.25
+	Ca
		804489 HSP90_CANAL (4-709): 0: 959: 81.75		Q59VX7_CANAL (13-848): 4.21e-85: 293: 12.80