HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: RIR4 (P49723)
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)
Gene: RNR4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	26217697, 15766533, 25452130, 31399574
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 345
+	Hs
		431570 HS90A_HUMAN (4-709): 0: 1015: 60.83		RIR2_HUMAN (20-345): 9.51e-163: 461: 47.40
+	Ca
		804503 HSP90_CANAL (4-709): 0: 959: 81.75		Q5A0L0_CANAL (1-345): 1.92e-166: 471: 54.31
+	Sc
		365619 HSP82_YEAST (1-709): 0: 984: 100.00		RIR2_YEAST (2-345): 4.69e-156: 445: 54.47
+	Sc
		456674 HSC82_YEAST (1-709): 0: 973: 94.64		RIR2_YEAST (2-345): 4.69e-156: 445: 54.47
+	Sc
		544066 HSC82_YEAST (1-709): 0: 973: 94.64		RIR4_YEAST (1-345): 5.01e-144: 412: 100.00