Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82
Interactor 2: AHA1 (Q12449)
Hsp90 co-chaperone AHA1 (Activator of Hsp90 ATPase protein 1)
Gene: AHA1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.993 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23396352, 24462205, 12604615, 15466438, 16429126, 15633294, 28851842, 12667448, 18719252, 37968396, 38705392, 24614167, 12504007, 15766533, 15879519, 26804907, 28363677, 27615124, 29930177, 28537252 and 7 others
more... |
| Identification Methods | fluorescent resonance energy transfer, cosedimentation in solution, surface plasmon resonance, atpase assay, affinity chromatography technology, pull down, two hybrid, biochemical, tandem affinity purification, two hybrid array |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aha1_N~HSP90, AHSA1~HSP90 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
